基本情况

张淑平(Shuping Zhang)，女，1993年6月出生，讲师，博士，主要从事的研究方向:

(1) 分子探针与生物成像研究:基于化学生物学领域从事有机生物传感的设计合成及生物成像 ；

(2) 诊疗一体: 具有诊治功能的“智能”近红外有机材料的设计与合成及荧光/光声引导的肿瘤光热治疗与预后分析研究。

E-Mail: shuingzhang@163.com

教育经历

2017/092020/06，广西师范大学，化学生物学，博士

2017/09‒2020/06，广西师范大学，化学，硕士

2013/09‒2017/06，衡阳师范学院，化学生物学，学士

工作经历

2023/06 至今 衡阳师范学院 化学与材料科学学院

科研成果                                                  

（一）论文：

1. Shuping Zhang, Hua Chen*, Hui Chen, Liping Wang, Xue Qin, Bang-Ping Jiang, Shi-Chen Ji, Xing-Can Shen* and Hong Liang. A General Approach to Design Dual Ratiometric Fluorescent and Photoacoustic Probe for Quantitatively Visualizing Tumor Hypoxia in Vivo. Angew. Chem. Int. Ed., 2022, 61, e202107076. (一级学科和专业硕士点学科提出的SCI顶刊，IF=16.823, SCI一区)

2. Shuping Zhang, Hua Chen*, Liping Wang, Chunli Liu, Li Liu, Yu Sun, Xing-Can Shen*. A simple strategy for simultaneously enhancing photostability and mitochondrial-targeting stability of near-infrared fluorophores for multimodal imaging-guided photothermal therapy. J. Mater. Chem. B, 2020. 9, 1089−1095. (IF=7.571, SCI二区)

3. Shuping Zhang, Fangyuan Cai, Bo Hou, Hua Chen, * Cunji Gao, Xing-can Shen* and Hong Liang. Constructing a far-red to near-infrared fluorescent probe for highly specific detection of cysteine and its bioimaging applications in living cells and zebrafish. New J. Chem., 2019, 43, 6696. (IF=3.925, SCI三区)

4. Xue Qin†, Shuping Zhang†, Xiaolu Guo, Xingyue Liu and Xing-Can Shen*. A cascading-response fluorescent probe for real-time monitoring pH during cysteine depletion process in pancreatic cancer cells. Front. Bioeng. Biotechnol., 2022, 10.3389/fbioe.2022.1062781. (IF=6.064, SCI二区)

5. Li Liu1, Jingyuan Xu1, Shuping Zhang, Hui Chen, Liping Wang, Xing-Can Shen, Hua Chen*. Rational design of dual ratiometric photoacoustic and fluorescent probe for reliable imaging and quantitative detection of endogenous CO during drug-induced liver injury and repair. Sensors and Actuators: B. Chemical. 2022, 367, 132171. (IF=9.221, SCI一区)

6. Changchun Wen, Hua Chen*， Xiaolu Guo, Zhaoxing Lin, Shuping Zhang, Xing-Can Shen, and Hong Liang*. Lysosome-Targeted Gold Nanotheranostics for In Situ SERS Monitoring pH and Multimodal Imaging-Guided Phototherapy. Langmuir 2021, 37, 569−577. (IF=4.331, SCI三区)

7. Fangyuan Cai, Bo Hou, Shuping Zhang, Hua Chen*, Shichen Ji, Xing-Can Shen* and Hong Liang. A chromenoquinoline-based two-photon fluorescent probe for the highly specific and fast visualization of sulfur dioxide derivatives in living cells and zebrafish. J. Mater. Chem. B, 2019, 7, 2493. (IF=7.571, SCI二区)

（二）专利：

1.陈华，张淑平，沈星灿，秦雪，一种双比率型半花菁类染料分子及其合成方法和应用. 中国发明专利，授权号：ZL202110765334.8.